However, after ventricular resection, the wound tissue adheres more strongly to the pericardial sac than after cryoinjury. It is possible that wound coverage by the epicardium is impaired by this adherence. Regeneration of myocardium removed by ventricular resection appears to occur via proliferation of differentiated cardiomyocytes. We likewise find that mature cardiomyocytes, expressing cardiac myosin light chain proliferate in response to cryoinjury and that proliferating cardiomyocytes invade the lesioned area. These data strongly indicate that NS 19504 necrotic lesions are repaired by proliferation of existing mature cardiomyocytes. Overall, our work shows that zebrafish cannot only restore surgically removed heart tissue, but also regenerate necrotic lesions. Since the latter type of injury is closer to the cardiac tissue damage seen in human patients, our results underscore the relevance of NSC 3852 research into the cellular and molecular mechanisms of natural heart regeneration in the zebrafish for efforts to devise regenerative therapies in humans. While we find that both ventricular resection and cryoinjury induced lesions are repaired using similar cellular mechanisms, we noticed a few temporal differences. Combined with the fact that we find setting of cryoinjuries to be less demanding of the experimenter and better tolerated by the fish than ventricular resection, we expect that this injury model will be highly valuable for future research into the molecular mechanisms of zebrafish heart regeneration. Plant growth and development are constrained by environmental stress conditions. Salt stress is one of the major environmental stresses in agriculture worldwide and affects productivity and crop quality. High salinity stress causes hyperosmotic stress, ion toxicity and nutrient deficiency, and can lead to molecular damage and even plant death. To respond and adapt to high salinity stress, plants have developed many strategies, such as selective ion uptake and exclusion, efficient detoxification by the antioxidant system, and the accumulation of osmotically protective matter. Numerous salt tolerance- relevant genes are induced in response to salt stress. The remorin protein family exists in all land plants, including angiosperms, gymnosperms, pteridophytes and bryophytes. The first remorin was discovered in potato in 1989 and named pp34 for its 34 kD molecular mass position in protein gels. The protein was renamed as remorin to indicate its ability to attach to the plasma membrane. Recently, more remorin genes have been identified from different plants. Remorins contain a conserved C-terminal region and a variable N-terminal region. The coiled-coil structure exists in the C-terminal region of remorin and is considered the family��s signature. The variable Nterminal region of remorin suggests different structures and functions.